Recently, the sodium (Na)/potassium (K) ratio was reported to be associated with blood pressure (BP). A Na/K ratio self-monitoring device using spot urine was established recently. Here, we assessed whether the urinary Na/K ratio change measured using the Na/K device was associated with BP change in a health checkup setting. We targeted 12,890 participants who attended the health checkup in Tome City, Miyagi between 2017 and 2018. Tome City introduced urinary Na/K ratio measurements during health checkups since 2017. For each year, we compared the baseline characteristics according to the urinary Na/K ratio and BP level. We assessed the relationship between change in urinary Na/K ratio and BP change using multiple regression analyses adjusted for age, sex, and change in body mass index (BMI) and alcohol intake. The average urinary Na/K ratio was significantly lower in 2018 than in 2017 (5.4 ± 3.0 to 4.9 ± 2.2, P < 0.01). The systolic BP of the participants in 2018 (130.9 ± 17.4 mmHg) was lower than that in 2017 (132.1 ± 17.9 mmHg). Moreover, the change in systolic BP and diastolic BP was positively associated with the change in urinary Na/K ratio. In conclusion, the association of the change in urinary Na/K ratio with hypertension and changes in systolic and diastolic BP can be explained by a change in alcohol intake, BMI, and urinary Na/K ratio. Therefore, measuring the urinary Na/K ratio in community settings is a potential population approach for counteracting hypertension.
Has just, it absolutely was stated that new salt (Na)/potassium (K) ratio try regarding the blood pressure level (BP) inside a cross-sectional studies [step 1,2,step 3,4]. This might be questioned because large Na and you may K consumption was identified are related to higher and you may lowest BP, correspondingly [5,six,7]. Concurrently, studies have been conducted into source thinking and you can things causing new Na/K ratio before seasons [8, 9].
Sodium/potassium proportion transform try associated with the blood pressure change: odds of inhabitants method for salt/potassium proportion lack of health checkup
When you look at the a residential district setting, it is sometimes complicated for us to evaluate the genuine Na intake while the Na consumption is generally examined from the twenty four-h pee collection. No matter if several equations having estimating Na consumption or K intake playing with everyday location pee have been recently mainly based, such equations aren’t right sufficient to provide viewpoints to the individuals [ten,eleven,12]. Furthermore, as equation needs calculating Na, K, and you may creatinine membership inside a lab, it entails weeks to obtain the results for anyone. Even when professionals are aware that salt protection is perfect for decreasing BP, he’s got not a way regarding determining its Na peak.
Has just, good Na/K proportion worry about-monitoring device having fun with place pee is actually situated . Although it failed to gauge the genuine Na intake level, it will promote opinions regarding your urinary Na/K harmony in a few minutes. Moreover, an interventional or observational studies with this screen suggested this was a useful device to help you imagine the fresh new urinary Na/K proportion [13, 14].
Hence, although we have no solution to gauge the Na/K proportion for the fitness checkup setup, i thought that evaluating the brand new urinary Na/K ratio inside the a healthcare checkup webpages could have the possibility to add opinions into the general population regarding their Na/K ratio that will impact effect change, change in action, Na/K ratio reduction, and you may BP prevention. Within research, i analyzed whether the urinary Na/K ratio changes mentioned toward Na/K proportion dimension tool is associated with the BP transform independent off confounding affairs eg body mass index (BMI) transform and change inside alcoholic drinks consumption and you can opposed new BP height and you may urinary Na/K ratio during the people localmilfselfies mobil sitesi height.